How do cellular machines unfold misfolded proteins?

Protein chains typically fold to function. Folding is a complex process and if done correctly leads to a unique functional fold topology for a given protein chain. Other topologies are also possible but are often non-functional ...

Protein determines life or death fate of stressed cells

Researchers discovered a new protein involved in the process that determines the fate of cells under stress and whether they fight to survive or sacrifice themselves for the greater good.

Do proteins remember?

A study integrating biological ideas and new computer science tools has uncovered novel associations between genetic coding and protein structure, which could potentially change the way we think about protein production in ...

Wapiti whistles sound like Ringwraith shrieks

For a majestic animal that looks equally at home as the monarch of the glen or astride the great American Plains, the wapiti's call is somewhat disconcerting. Sounding more like the shrieking cries of a Lord of the Rings ...

How protein aggregation occurs in cells

Published in the Molecular Cell journal on July 19, a research study out of the Hatters Laboratory showed inappropriate protein aggregation is linked to poor outcomes for cell health and survival—especially in neurons in ...

page 13 from 19