KAIST researchers have used an X-ray method to track how proteins fold, which could improve computer simulations of this process, with implications for understanding diseases and improving drug discovery. Their findings were ...
Molecular & Computational biology
Jul 9, 2020
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27
Misfolded proteins must be promptly eliminated as they can form toxic aggregates in cells. LMU biologists have studied how this process is triggered in mitochondria and identified a general alarm signal that activates it.
Cell & Microbiology
Aug 27, 2019
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7
Researchers have discovered a second giant pore for the transport of folded proteins in certain cell organelles, i.e. peroxisomes. Five years ago, the group already described the first giant pore. The team headed by Prof ...
Cell & Microbiology
Dec 4, 2015
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5
Proteins are the workhorses of the cell and thus responsible for almost all biological functions including metabolism, signal transmission or the determination of the cell's shape. However, before they can fulfill their various ...
Cell & Microbiology
May 9, 2014
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0
A study developed by researchers at the Faculty of Physics of the University of Barcelona (UB), published in the journal Physical Review Letters, describes the contribution of water to the three-dimensional structure of proteins ...
Condensed Matter
Sep 21, 2015
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117
Biophysicists at JILA have measured protein folding in more detail than ever before, revealing behavior that is surprisingly more complex than previously known. The results suggest that, until now, much about protein behavior ...
Biochemistry
Mar 2, 2017
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18
Researchers propose "Oritatami" as a mathematical model of the cotranscriptional folding of RNA in order to widen applications of RNA origami—one of the most significant experimental breakthroughs in molecular self-assembly.
Cell & Microbiology
Jul 6, 2016
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12
To make paper, manufacturers must break down cellulose (chunks of wood pulp), a process that currently requires large amounts of energy and toxic chemicals like chlorine. Nature performs the same task using enzymes, non-toxic ...
Materials Science
Jan 30, 2014
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0
Chaperones are molecular helpers that assist other proteins with folding. One such chaperone is the so-called heat shock protein 60 (Hsp60). This protein forms structures in mitochondria that resemble barrels in which folding ...
Biochemistry
May 12, 2015
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21
A new study from Tel Aviv University has discovered that a known practice in information technology can also be applied to chemistry. Researchers found that to enhance the sampling in chemical simulations, all you need to ...
Analytical Chemistry
Feb 12, 2024
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33
