Ferrocene is an emergent organic-metal hybrid compound, and its accidental discovery has led to the rapid development of organometallic chemistry. Aside from its interesting structure, which consists of an iron atom sandwiched ...
Analytical Chemistry
Aug 29, 2023
0
343
Many of the most promising new pharmaceuticals coming along in the drug development pathway are hydrophobic by nature—that is, they repel water, and are thus hard to dissolve in order to make them available to the body. ...
Biochemistry
Nov 28, 2023
0
59
Penn Engineers have pioneered a new way to visualize the smallest protein clusters, skirting the physical limitations of light-powered microscopes and opening new avenues for detecting the proteins implicated in diseases ...
Biotechnology
Feb 8, 2024
0
55
Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins—a new but largely unrealized approach to the treatment ...
Cell & Microbiology
Mar 22, 2024
0
30
Gun-toting youths watch over a street in a Rio de Janeiro slum hit hard by drug trafficking, but walk a bit further and this rough area also boasts the largest urban vegetable garden in Latin America.
Ecology
May 21, 2022
0
36
Led by Director Chang Sukbok, scientists from the Center for Catalytic Hydrocarbon Functionalizations within the Institute for Basic Science (IBS) have made a significant advancement in the synthesis of β-lactam scaffolds, ...
Biochemistry
Aug 24, 2023
0
101
Scientists have developed two new drug candidates for potentially treating addiction and depression, modeled on the pharmacology of a traditional African psychedelic plant medicine called ibogaine. At very low doses, these ...
Biochemistry
May 2, 2023
2
85
Most drugs are small molecules that bind firmly to a specific target—some molecule in human cells that is involved in a disease—in order to work. For example, a cancer drug's target might be a molecule that is abundant ...
Biochemistry
Sep 29, 2023
0
59
A mutated protein causes the genetic disease cystic fibrosis. Now, researchers have solved the structure of the protein and how certain drugs bind to it, unveiling their mode of action.
Cell & Microbiology
Jan 7, 2022
0
590
Deep learning has radically changed the field of artificial intelligence. Now neural networks are revolutionizing the way that we discover new drugs. We talk to Francesca Grisoni, assistant professor at the department of ...
Biotechnology
Sep 16, 2021
0
240
