Fast folding for synthetic peptides and microproteins
Certain types of peptides and microproteins for drug discovery research can be made more efficiently and quickly using a reaction solvent that helps mimic nature's way.
Certain types of peptides and microproteins for drug discovery research can be made more efficiently and quickly using a reaction solvent that helps mimic nature's way.
Biochemistry
Mar 22, 2024
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Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal ...
Cell & Microbiology
Jan 2, 2024
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66
Editors and reviewers of the journal Green Chemistry have highlighted a new study from the University of Texas at Arlington investigating how to make common chemical techniques more environmentally friendly as one of its ...
Materials Science
Dec 20, 2023
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Most diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great ...
Biochemistry
Dec 11, 2023
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A combined team of biomedical researchers from Novartis Institutes for Biomedical Research and Microsoft Research AI4Science has made inroads into teaching AI systems how to find new medicines. In their study, reported in ...
Azobenzenes are incredibly versatile and have many potential uses, such as in making tiny machines and improving technology as well as making light controllable drugs. This molecule can switch between two different forms ...
Biochemistry
Sep 21, 2023
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167
Membrane proteins play a pivotal role in various cellular functions and are key targets for pharmaceutical interventions. In fact, approximately 60% of drugs currently available on the market target these specific proteins. ...
Molecular & Computational biology
Sep 7, 2023
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Myocardial infarction, the number one cause of sudden death in adults and the number two cause of death in Korea, is a deadly disease with an initial mortality rate of 30%, and about 5%–10% of patients die even if they ...
Bio & Medicine
Aug 25, 2023
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A highly versatile family of receptors found on the surface of our cells plays a massive role in the multibillion-dollar field of drug discovery. Called G protein-coupled receptors, or GPCRs, they also facilitate a staggering ...
Cell & Microbiology
Jul 5, 2023
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A new study suggests that cells preparing to divide can reverse this process and return to a resting state, challenging long-held beliefs about cell division. If interrupted early in their preparation to divide, cells were ...
Cell & Microbiology
Jul 5, 2023
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