Transforming drug discovery with AI: New program transforms 3D information into data that typical models can use
A new AI-powered program will allow researchers to level up their drug discovery efforts.
A new AI-powered program will allow researchers to level up their drug discovery efforts.
Biotechnology
Jun 21, 2024
0
56
A mechanism that could help scientists harness enzymes for use in drug discovery has been discovered in a research breakthrough at the University of Birmingham.
Molecular & Computational biology
Jun 20, 2024
0
36
A laboratory-grown mini liver model uniquely created with liver cells and a synthetic nanoscaffold has shown to be effective in mimicking the liver, promising a new and more effective testing method for medicines that is ...
Bio & Medicine
Jun 20, 2024
0
26
An innovative project to re-purpose existing drugs for their potential as antibiotics has uncovered a highly promising candidate with a potent and unique way of killing drug resistant bacteria.
Biochemistry
Jun 19, 2024
0
66
The use of AI to streamline drug discovery is exploding. Researchers are deploying machine-learning models to help them identify molecules, among billions of options, that might have the properties they are seeking to develop ...
Biochemistry
Jun 17, 2024
0
56
Australian researchers, led by Monash University, have invented a new artificial intelligence (AI) tool which is poised to reshape virtual screening in early stage drug discovery and enhance scientists' ability to identify ...
Biochemistry
Jun 17, 2024
0
31
A relatively simple peptide modification could unlock a whole class of targets for drug discovery, new research shows.
Analytical Chemistry
Jun 7, 2024
0
0
Scientists at the University of Wisconsin–Madison have developed the most sensitive method yet for detecting and profiling a single molecule—unlocking a new tool that holds potential for better understanding how the building ...
Analytical Chemistry
May 30, 2024
0
326
Organosulfur compounds, organic compounds containing sulfur, are vital in biological processes and research fields like pharmaceuticals, biomedical imaging, agriculture, and electronics. Compounds like phenothiazine, thianthrene ...
Biochemistry
May 23, 2024
0
2
Proteins are like tiny machines in our bodies, helping with almost everything we do, including breaking down food, carrying messages between cells, and building and repairing tissues, like muscles and skin.
Molecular & Computational biology
May 16, 2024
0
1
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are discovered and/or designed.
In the past most drugs have been discovered either by identifying the active ingredient from traditional remedies or by serendipitous discovery. A new approach has been to understand how disease and infection are controlled at the molecular and physiological level and to target specific entities based on this knowledge.
The process of drug discovery involves the identification of candidates, synthesis, characterization, screening, and assays for therapeutic efficacy. Once a compound has shown its value in these tests, it will begin the process of drug development prior to clinical trials.
Despite advances in technology and understanding of biological systems, drug discovery is still a lengthy, "expensive, difficult, and inefficient process" with low rate of new therapeutic discovery. Information on the human genome, its sequence and what it encodes has been hailed as a potential windfall for drug discovery, promising to virtually eliminate the bottleneck in therapeutic targets that has been one limiting factor on the rate of therapeutic discovery.[citation needed] However, data indicates that "new targets" as opposed to "established targets" are more prone to drug discovery project failure in general[citation needed] This data corroborates some thinking underlying a pharmaceutical industry trend beginning at the turn of the twenty-first century and continuing today which finds more risk aversion in target selection among multi-national pharmaceutical companies.[citation needed]
This text uses material from Wikipedia, licensed under CC BY-SA