Snakebites cause around 100,000 deaths worldwide every year. Researchers at the Technical University of Munich (TUM) have investigated how the toxin emerged between 50 and 120 million years ago through the modification of ...
Evolution
Oct 9, 2023
0
131
Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs. Details on the findings, which were reported in the ...
Molecular & Computational biology
Sep 7, 2023
0
81
Membrane proteins play a pivotal role in various cellular functions and are key targets for pharmaceutical interventions. In fact, approximately 60% of drugs currently available on the market target these specific proteins. ...
Molecular & Computational biology
Sep 7, 2023
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1
Led by Director Chang Sukbok, scientists from the Center for Catalytic Hydrocarbon Functionalizations within the Institute for Basic Science (IBS) have made a significant advancement in the synthesis of β-lactam scaffolds, ...
Biochemistry
Aug 24, 2023
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101
Chemical structures called cyclopropanes can increase the potency and fine-tune the properties of many drugs, but traditional methods to create this structure only work with certain molecules and require highly reactive—potentially ...
Biochemistry
Aug 3, 2023
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81
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With ...
Molecular & Computational biology
Aug 1, 2023
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235
Ion channels play a crucial role in many cellular processes, including neuronal communication, muscle contraction or cell proliferation.
Cell & Microbiology
Aug 1, 2023
0
1
Researchers have discovered a new stress signaling system that enables bacteria cells to adapt and protect themselves against the immune system and certain antibiotics.
Cell & Microbiology
Jul 19, 2023
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1
Chemists at King's College London have made a breakthrough in the way they develop artificial helix shapes for the amino acids that constitute proteins. These new synthetic shapes have the potential to transform processes ...
Analytical Chemistry
Jul 19, 2023
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14
In a cutting-edge discovery, published in the Journal of the American Chemical Society, Florey scientists have solved a long-standing problem: the need for an affordable, simple way to make peptide-based drugs that hold their ...
Biochemistry
Jul 17, 2023
0
61
