(Phys.org) -- New drug candidates require testing in animal models prior to approval for clinical use. A recently developed antagonist based on a bicyclic peptide inhibited the human serine protease plasma kallikrein potently ...
Biochemistry
Apr 13, 2012
0
0
Chemists at The Scripps Research Institute (TSRI) have devised a greatly improved technique for making amino acids not found in nature. These "unnatural" amino acids traditionally have been very difficult to synthesize, but ...
Biochemistry
Mar 13, 2014
0
0
Scripps Research scientists have solved a major problem in chemistry and drug development by using droplet-sized 'miniecosystems' to quickly see if a molecule can function as a potential therapeutic.
Analytical Chemistry
Jun 18, 2018
0
101
Biting into a chili pepper causes a burning spiciness that is irresistible to some, but intolerable to others. Scientists exploring the chili pepper's effect are using their findings to develop a new drug candidate for many ...
Biochemistry
Aug 20, 2014
0
0
A powerful computational technique used by the pharmaceutical industry to expedite new drug development has just received a performance boost. Chandra Verma and his co-workers at the A*STAR Bioinformatics Institute in Singapore ...
Biochemistry
Jan 30, 2013
0
0
A unique computer technology that opens up the discovery of smarter drugs to treat major illnesses including heart disease has been invented by University of Strathclyde scientists.
Other
Aug 26, 2013
0
0
Drug discovery may bring to mind images of white lab coats and pipettes, but when Henry Lin, PhD, recently set out to find a better opioid with fewer side effects, his first step was to fire up the computers.
Biochemistry
Apr 6, 2017
0
9
The lab of Rice University synthetic organic chemist K.C. Nicolaou has reported the streamlined total synthesis of delta12-prostaglandin J3, a molecule previously claimed to kill leukemic cancer cells.
Biochemistry
May 23, 2016
0
36
The Ebola virus is among the deadliest viruses on the planet, killing up to 90% of those infected, and there are no approved vaccines or effective therapies. A study published by Cell Press on May 7th in the Biophysical Journal ...
Cell & Microbiology
May 7, 2013
0
0
(PhysOrg.com) -- Researchers have achieved a feat drug developers had thought difficult, if not impossible, discovering a compound that blocks the functioning of a key developmental protein by binding to an “undruggable” ...
Jan 19, 2009
0
0
