Physical mechanisms explaining DNA and RNA twist changes

The double-helix structure of DNA is deformed by environmental stimuli, which will then affect gene expression, and eventually trigger a sequence of cellular processes. Recent research led by a physicist from City University ...

Quantum mechanics could explain why DNA can spontaneously mutate

The molecules of life, DNA, replicate with astounding precision, yet this process is not immune to mistakes and can lead to mutations. Using sophisticated computer modeling, a team of physicists and chemists at the University ...

Autonomous nanomachines inspired by nature

Inspired by the way molecules interact in nature, UNSW medical researchers engineer versatile nanoscale machines to enable greater functional range.

The first stages of DNA evolution

One fundamental question in the field of the Origin of Life is how the first molecules of DNA replicated and evolved on the primordial Earth, more than 4 billion years ago. Before the emergence of the first cells or any other ...

Cryo-EM reveals how '911' molecule helps fix damaged DNA

When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem—a failsafe that is critical to maintaining health and staving off disease.

Researchers uncover genetic 'bridge' to leukemia progression

For cells to thrive, a complex network of three-dimensional structures assembles to read, copy and produce the genetic materials (DNA) needed for cellular function. Understanding how these structures form, and what happens ...

DNA design brings predictability to polymer gels

Scientists in Japan have made a tuneable, elastic and temperature-sensitive gel by using complementary DNA strands to connect star-shaped polymer molecules together. The gel, and the method used to develop it, could lead ...

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