Related topics: dna sequences · protein

Transcription factors may inadvertently lock in DNA mistakes

Transcription factor proteins are the light switches of the human genome. By binding to DNA, they help turn genes 'on' or 'off' and start the important process of copying DNA into an RNA template that acts as a blueprint ...

Unraveling the genome in 3-D space

Proper folding of extremely long chromosomal DNA molecules is crucial for the correct functioning of the cell. Scientists from the Gerlich lab at IMBA—Institute of Molecular Biotechnology of the Austrian Academy of Sciences—developed ...

RNA information transfer could be used in repairing DNA

Genomes are routinely subjected to DNA damage. But most cells have DNA repair systems that enforce genome stability and, ideally, prevent diseases like cancer. The trouble gets serious when these systems break down. When ...

Harnessing DNA molecules for disease detection and electronics

DNA molecules express heredity through genetic information. However, in the past few years, scientists have discovered that DNA can conduct electrical currents. This makes it an interesting candidate for roles that nature ...

Barcoding long DNA quantifies CRISPR effects

Current sequencing techniques lack the sensitivity to detect rare gene mutations in a pool of cells, which is particularly important, for example, in early cancer detection. Now, scientists at KAUST have developed an approach, ...

Molecular forces: The surprising stretching behavior of DNA

When large forces act on a heavy beam, for example, in bridge construction, the beam will be slightly deformed. Calculating the relationship between forces, internal stresses and deformations is one of the standard tasks ...

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