Researchers at the Garvan Institute of Medical Research have uncovered a new form of DNA modification in the genome of zebrafish, a vertebrate animal that shares an evolutionary ancestor with humans ~400 million years ago.
Biotechnology
Dec 4, 2020
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164
Similar to genetic mutations, epigenetic changes, i.e. gene modifications that do not occur on the primary DNA sequence, sometimes arise accidentally in plants and can be transmitted across generations. Using trees as a model, ...
Plants & Animals
Nov 18, 2020
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68
For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a ...
Evolution
Nov 18, 2020
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45
A research team from Cologne has discovered that a change in the DNA structure—more precisely in the chromatin—plays a decisive role in the recovery phase after DNA damage. The key is a double occupation by two methyl ...
Cell & Microbiology
Oct 13, 2020
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283
Some of the genetic differences that have arisen between domesticated chickens and their wild ancestors, the red junglefowl, are linked to epigenetic changes, according to a new study published in Nature Ecology & Evolution. ...
Plants & Animals
Sep 21, 2020
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213
A team of researchers from New Jersey Institute of Technology (NJIT) and Children's Hospital of Philadelphia (CHOP) have developed an algorithm through machine learning that helps predict sites of DNA methylation—a process ...
Biotechnology
Aug 6, 2020
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196
There are about 75 different types of cells in the human brain. What makes them all different? Researchers at Baylor College of Medicine have developed a new set of computational tools to help answer this question. Although ...
Biotechnology
Jul 1, 2020
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139
Scientists at EMBL Rome unveil the mechanism behind the most studied epigenetic modification.
Biotechnology
Jun 11, 2020
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110
While the first genome-wide DNA methylation map in mammalian cells was established over 10 years ago, such maps only provide snapshots and do not inform about the actual dynamics of this epigenetic mark. Researchers from ...
Biotechnology
Jun 2, 2020
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16
When the machinery that guides the transition of stem cells to somatic cells doesn't shut down properly, cells can become cancerous. Identifying the mechanisms that impede those processes would offer scientists a target for ...
Cell & Microbiology
Feb 11, 2020
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111
