Related topics: cancer cells · cells · dna repair · breast cancer · cancer

'Cowcatcher' enzyme fixes single-strand DNA

Every time one of your cells divides, it exposes its most essential component to great danger: its genome, the sum total of all its genetic information, embodied in the double-stranded helix of DNA. Prior to cell division, ...

Researchers clarify how DNA damage signaling works

The DNA molecule is chemically unstable, giving rise to DNA lesions of various kinds. That is why DNA damage detection, signaling and repair, collectively known as the DNA damage response, are needed. The DNA damage response ...

Nanoparticles may cause DNA damage across a cellular barrier

(PhysOrg.com) -- Scientists have shown in the laboratory that metal nanoparticles damaged the DNA in cells on the other side of a cellular barrier. The research, by the University of Bristol, is published online this week ...

How a single enzyme unleashes a complex DNA repair process

Our DNA is constantly exposed to damaging factors that can lead to aging and age-related diseases such as cancer. PARP1 is an important enzyme that facilitates the response to DNA damage by attaching chemical groups called ...

Timing is key for bacteria surviving antibiotics

For bacteria facing a dose of antibiotics, timing might be the key to evading destruction. In a series of experiments, Princeton researchers found that cells that repaired DNA damaged by antibiotics before resuming growth ...

DNA chip offers big possibilities in cell studies

A UT Dallas physicist has developed a novel technology that not only sheds light on basic cell biology, but also could aid in the development of more effective cancer treatments or early diagnosis of disease.

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