New technique lets doctors predict disease severity

An international team of researchers has found a way to diagnose disease and predict patient outcomes simply by measuring unbelievably small changes in interactions between molecules inside the body. The simple new technique ...

Fungi can change quickly, pass along infectious ability

Fungi have significant potential for "horizontal" gene transfer, a new study has shown, similar to the mechanisms that allow bacteria to evolve so quickly, become resistant to antibiotics and cause other serious problems.

Architecture of rod sensory cilium disrupted by mutation

Using a new technique called cryo-electron tomography, two research teams at Baylor College of Medicine have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium ...

How proteins assemble may have underappreciated role in disease

Thanks to advances in genomics in recent decades, researchers now know the genetic mutations responsible for many diseases. However, researchers often still do not know how the mutation leads to the disease—what it changes ...

Worm research defines the role of multiple disease genes in cilia

(PhysOrg.com) -- University College Dublin researchers led by Conway Fellow, Dr Oliver Blacque have outlined how cilia disease gene products regulate important aspects of early cilium formation and the integrity of the ciliary ...

Uncovering hidden mitochondrial mutations in single cells

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies ...

page 7 from 9