Northwestern Medicine scientists have developed a more effective way of creating nanotherapeutic vaccines and medicines, according to a new study published in ACS Nano.
Bio & Medicine
Oct 31, 2023
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16
A team of scientists has developed a new solution for the treatment of rheumatoid arthritis (RA). The work has been published in Nature Nanotechnology.
Bio & Medicine
Oct 26, 2023
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22
Messenger RNA (mRNA) vaccines are revolutionizing the therapy of cancer. They can be flexibly developed in a short period of time, allowing transient expression of multiple antigens for safe and efficient immunization. A ...
Bio & Medicine
Oct 16, 2023
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19
Human immune cells are capable of coordinating their own movement more independently than previously thought. InFLAMES researcher Jonna Alanko has discovered that immune cells do not just passively follow the chemical cues ...
Cell & Microbiology
Sep 6, 2023
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0
Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells—which play a key role in immune response—that eradicated tumors and prevented their ...
Bio & Medicine
Jul 27, 2023
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17
Johns Hopkins Medicine scientists say they have developed a nanoparticle—an extremely tiny biodegradable container—that has the potential to improve the delivery of messenger ribonucleic acid (mRNA)-based vaccines for ...
Bio & Medicine
Jun 28, 2023
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21
In addition to an antigen, many vaccines also contain substances, called adjuvants, which stimulate the immune system. By using computer-aided molecular design and machine learning, a Chinese research team has now developed ...
Biochemistry
Mar 27, 2023
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10
Cancer immunotherapies, such as immune checkpoint inhibition therapy, have been attracting attention in recent years as new methods for treating cancer. However, immune checkpoint inhibition therapy is only effective in 20%–30% ...
Bio & Medicine
Oct 31, 2022
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5
Cancer cells use an unusual mechanism to migrate into new tissue and form metastases there. The same process probably also keeps some immune cells on their toes. This is the result of a recent study led by the University ...
Cell & Microbiology
Oct 14, 2022
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83
A team of researchers affiliated with multiple institutions in China, the U.S. and Brazil has used "handedness" in chiral gold nanoparticles to enhance immune response to the influenza virus in mice. The group describes their ...
Dendritic cells (DCs) are immune cells that form part of the mammalian immune system. Their main function is to process antigen material and present it on the surface to other cells of the immune system, thus functioning as antigen-presenting cells.
Dendritic cells are present in small quantities in tissues that are in contact with the external environment, mainly the skin (where there is a specialized dendritic cell type called Langerhans cells) and the inner lining of the nose, lungs, stomach and intestines. They can also be found in an immature state in the blood. Once activated, they migrate to the lymphoid tissues where they interact with T cells and B cells to initiate and shape the adaptive immune response. At certain development stages they grow branched projections, the dendrites, that give the cell its name. However, these do not have any special relation with neurons, which also possess similar appendages. Immature dendritic cells are also called veiled cells, in which case they possess large cytoplasmic 'veils' rather than dendrites.
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