Condensins mutually interact to fold DNA into a zigzag structure

DNA in a cell is comparable to tangled spaghetti strands on a plate. To be able to divide DNA neatly between the two daughter cells during cell division, the cell organises this tangle into tightly packed chromosomes. A protein ...

Stable conditions during cell division

Errors during cell division can trigger the development of cancer. No wonder that this central process is controlled by multiple regulators and guards. Alex Bird's research group at the Max Planck Institute of Molecular Physiology ...

A scaffold at the center of our cellular skeleton

All animal cells have an organelle called a centrosome, which is essential to the organization of their cell skeleton. The centrosome plays fundamental roles, especially during cell division, where it allows equal sharing ...

How plants harness 'bad' molecules for good ends

When most people think of a plant, they picture stems, leaves, flowers, and all the parts that are visible above ground. But Duke biologist Philip Benfey is more interested in the hidden half of the plant that is buried beneath ...

Scientists detail how chromosomes reorganize after cell division

Researchers have discovered key mechanisms and structural details of a fundamental biological process—how a cell nucleus and its chromosomal material reorganizes itself after cell division. The new findings in chromosomal ...

Researchers find 'protein-scaffolding' for repairing DNA damage

At the University of Copenhagen, researchers have discovered how some types of proteins stabilize damaged DNA and thereby preserve DNA function and integrity. This new finding also explains why people with inborn or acquired ...

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