The first line of defense against skin cancer is the ability to repair DNA damage caused by UV light. The XPA protein plays an important role in the repair of certain DNA damage, and mutations in this protein have been implicated ...
Biochemistry
Dec 7, 2017
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3
The heredity substance DNA is the blueprint of our life. Like an instruction manual it contains all the information needed for cells and the body to function properly. In the process, the DNA is always exposed to threats ...
Cell & Microbiology
Aug 30, 2017
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3
We humans like to think our DNA is well-protected in the nucleus of each cell. But it's a hard life for the hard-working genetic code.
Cell & Microbiology
May 11, 2017
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9
An international collaboration between Osaka University and the Friedrich Miescher Institute for Biomedical Research (FMI) in Switzerland is investigating the repair process of a serious form of DNA damage that can lead to ...
Biotechnology
Jan 19, 2017
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4
Aging in part is the result of oxidative damage to proteins caused by free radicals, a byproduct of interaction of our bodies and radiation such as sunlight. A new study by Yale scientists provides some clues into how this ...
Biochemistry
Jul 22, 2016
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6
In bacteria, toxin-antitoxin systems consist of a set of two closely linked genes. Situated on the same chromosome, they encode both a protein 'poison' and a counteracting 'antidote'. Under normal conditions, the antitoxin ...
Cell & Microbiology
Feb 22, 2016
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6
Messenger (mRNA) molecules are a key component of protein biosynthesis. They are first transcribed as a "working copy" of the DNA and then translated into protein molecules. RNA-binding proteins such as RC3H1 (also known ...
Cell & Microbiology
Jul 31, 2015
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27
A protein that helps embryonic stem cells (ESCs) retain their identity also promotes DNA repair, according to a study in The Journal of Cell Biology. The findings raise the possibility that the protein, Sall4, performs a ...
Cell & Microbiology
Mar 2, 2015
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14
Biological molecules such as proteins can contain hundreds of thousands of atoms, which makes it very difficult to understand their function in detail. Identifying the exact atomic structure of these complex molecules is ...
General Physics
Jul 18, 2014
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The packaging of a gene has a major impact on its functional state and must be precisely controlled. A novel blend of methods has unveiled the architecture of a large protein complex that modulates DNA packing, and hints ...
Cell & Microbiology
Sep 16, 2013
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