Messenger (mRNA) molecules are a key component of protein biosynthesis. They are first transcribed as a "working copy" of the DNA and then translated into protein molecules. RNA-binding proteins such as RC3H1 (also known ...
Cell & Microbiology
Jul 31, 2015
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27
A hitherto unknown mechanism for DNA folding is described in a study in Nature published by researchers from Karolinska Institutet and the Max Planck Institute for Biophysics. Their findings provide new insights into chromosomal ...
Cell & Microbiology
Apr 19, 2023
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21
The first line of defense against skin cancer is the ability to repair DNA damage caused by UV light. The XPA protein plays an important role in the repair of certain DNA damage, and mutations in this protein have been implicated ...
Biochemistry
Dec 7, 2017
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3
Mycobacterium tuberculosis is arguably the world's most successful infectious agent because it knows how to avoid elimination by slowing its own growth to a crawl. Now, a report in the July 10 issue of the journal Cell, a ...
Cell & Microbiology
Jul 9, 2009
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0
Transcription factors regulate gene expression by binding specific sequences on DNA, which is an essential step to producing messenger RNAs from protein-coding genes. Denes Hnisz's lab, in collaboration with Martin Vingron's ...
Cell & Microbiology
Jul 5, 2024
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2
To fight infections cells in the immune system play a dangerous game with their own genes. Damaging genes allows B cells to make antibodies that are specifically equipped to target to specific causes of illness, but damaging ...
Cell & Microbiology
Sep 13, 2017
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2
The heredity substance DNA is the blueprint of our life. Like an instruction manual it contains all the information needed for cells and the body to function properly. In the process, the DNA is always exposed to threats ...
Cell & Microbiology
Aug 30, 2017
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3
Attaching chains of the small molecule ADP-ribose to proteins is important for a cell's survival and the repair of DNA damage, making this process a promising target for the development of new cancer drugs. Researchers have ...
Cell & Microbiology
Mar 12, 2013
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3
In animals, DNA damage could lead to cancers. Although plants live for a long time without cancers, their growth is always challenged by many environmental factors, such as radiation, salinity, heavy metals and flooding, ...
Molecular & Computational biology
Nov 9, 2022
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10
An international collaboration between Osaka University and the Friedrich Miescher Institute for Biomedical Research (FMI) in Switzerland is investigating the repair process of a serious form of DNA damage that can lead to ...
Biotechnology
Jan 19, 2017
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4
