Structural knowledge of the DNA repair complex

New Danish research provides mechanistic insight into how DNA is monitored and repaired if damage occurs. The results may eventually help to improve the treatment of certain types of cancer, as the DNA repair complex provides ...

Tissue damage is key for cell reprogramming

Cell reprogramming does not happen exactly as we thought. In the pages of the journal Science, a team from the Spanish National Cancer Research Centre (CNIO) has shown that tissue damage is a relevant factor for cells to ...

A new energy source within the cells

All our cells require the small molecule, ATP, generated in the mitochondria to cover the energy required for cell metabolism, dynamics and growth. To a lower extent and particularly in cancer cells, ATP can also be generated ...

New protein gel for tissue regeneration

The human body can repair a lot of tissue damage itself. But sometimes, for instance in case of operations of wounds, it needs help. In her doctoral research, Gosia Wlodarczyk-Biegun developed a protein polymer that provides ...

Controls of specialization unraveled

Two phases of the cell cycle of human embryonic stem cells have been shown, for the first time, to actively employ pathways that maintain pluripotency—the potential to develop into almost any type of cell in the body.

A novel DNA damage alarm

How does our body keep its DNA intact? Researchers at Erasmus MC have just found a new piece of this puzzle. They discovered a novel alarm that cells use to signal DNA damage. "We already knew that DNA damage triggers an ...

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