A protein that helps embryonic stem cells (ESCs) retain their identity also promotes DNA repair, according to a study in The Journal of Cell Biology. The findings raise the possibility that the protein, Sall4, performs a ...
Cell & Microbiology
Mar 2, 2015
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Our genomes encounter DNA damaging events continuously. As damage accumulates, our cells react and stop the cell division process, giving repair mechanisms time to act. To achieve this, two master protein kinases called ATR ...
Cell & Microbiology
Dec 19, 2014
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Promoting the guided regeneration of nerve cells could transform the treatment of a vast range of debilitating conditions, including brain injuries, nerve damage and degenerative neurological diseases. Electrically stimulating ...
Polymers
Oct 31, 2014
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Cells are generally able to repair spontaneous damage that arises in their genetic material. Unfortunately, the DNA repair process is not perfect and sometimes, damaged DNA gets passed on to newly made cells. A team of researchers ...
Cell & Microbiology
Oct 8, 2014
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An animal biologist says poor nutrition results in genetic damage to sperm cells and lower sperm motility for rams.
Plants & Animals
Aug 20, 2014
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Repair of DNA lesions is essential for mammalian development. Notably, DNA lesions in cells caused by genotoxic agents results in arrest of cell cycle and ultimately in cell death. In response, DNA polymerase ζ (Polζ) is ...
Biochemistry
Jun 25, 2014
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Imagine filling a hole in your heart by regrowing the tissue. While that possibility is still being explored in people, it is a reality in salamanders. A recent discovery that newt hearts can regenerate may pave the way to ...
Plants & Animals
Apr 29, 2014
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Cell reprogramming converts specialised cells such as nerve cells or skin cells towards an embryonic stem cell state. This reversal in the evolutionary development of cells also requires a reversal in the biology of telomeres, ...
Cell & Microbiology
Apr 21, 2014
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Horses suffering from neurological conditions similar to those that affect humans could be helped by a breakthrough from stem cell scientists.
Cell & Microbiology
Mar 4, 2014
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The molecular pathways involved in the cell cycle are complex and difficult to control. Better understanding of cell control mechanisms, and why they go wrong in cancer, could help open the door to more effective cancer drug ...
Cell & Microbiology
Jan 29, 2014
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