Team develops key improvement to cryo-electron microscopy

The scientists who received the 2017 Nobel Prize in chemistry were honored for their development of a technique called cryo-electron microscopy, or cryo-EM. The technology was revolutionary because it enabled scientists to ...

Discovery offers starting point for better gene-editing tools

CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases. However, there is a last-mile problem—these tools need to be effectively ...

New technology solves mystery of respiration in Tetrahymena

Tetrahymena, a tiny single celled-organism, turns out to be hiding a surprising secret: it's doing respiration—using oxygen to generate cellular energy—differently from other organisms such as plants, animals or yeasts. ...

Biochemists trap and visualize an enzyme as it becomes active

How do you capture a cellular process that transpires in the blink of an eye? Biochemists at MIT have devised a way to trap and visualize a vital enzyme at the moment it becomes active—informing drug development and revealing ...

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