New technique boosts cryo-electron microscopy clarity, safety

When scientists needed to visualize the structure of the spike protein, which coronaviruses use to infiltrate human cells, they turned to cryo-electron microscopy. One of the most powerful imaging tools in a researcher's ...

Chimeric viruses unearth hidden gems in dengue virus structure

In a recent study, Australian scientists used an original approach to resolve the 3D structure of flaviviruses with an unprecedented level of detail, identifying small molecules known as 'pocket factors' as new therapeutic ...

Machine-learning model helps determine protein structures

Cryo-electron microscopy (cryo-EM) allows scientists to produce high-resolution, three-dimensional images of tiny molecules such as proteins. This technique works best for imaging proteins that exist in only one conformation, ...

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