A method for predicting antiviral drug or vaccine targets

A novel method to predict the most promising targets for antiviral drugs or vaccines is based on the conformational changes viral glycoproteins go through during the process of recognition and binding to the host cell. This ...

Nanopore reveals shape-shifting enzyme linked to catalysis

University of Groningen scientists have observed the characteristics of a single enzyme inside a nanopore. They learned that the enzyme can exist in four different folded states, or conformers, that play an active role in ...

The ABC of ribosome recycling

Ribosomes, the essential machinery used for protein synthesis is recycled after each one round of translation. An enzyme called ABCE1 is responsible for this process and turns out to be remarkably plastic as LMU biophysicists ...

New method enables 'photographing' of enzymes

Scientists at the University of Bonn have developed a method with which an enzyme at work can be "photographed". Their method makes it possible to better understand the function of important biomolecules. The researchers ...