Just as healthy organs are vital to our well-being, healthy organelles are vital to the proper functioning of the cell. These subcellular structures carry out specific jobs within the cell; for example, mitochondria power ...
Cell & Microbiology
Jan 1, 2024
0
121
In 1983, scientists discovered hexasomes—a unique molecular structure that helps cells package their DNA. Now, a study conducted by the Eustermann group at EMBL Heidelberg has shed light on how DNA packaging into hexasomes ...
Cell & Microbiology
Jul 13, 2023
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1
In almost every human cell, 2 meters of DNA has to fit within a nucleus that is just 8 millionths of a meter wide. Like wool around a spool, the extreme space challenge requires DNA to wrap around structural proteins called ...
Evolution
Jun 9, 2022
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47
Scientists from Tokyo Metropolitan University have uncovered a unique mechanism where two transcription factors stabilize each other's binding to DNA in fission yeast. They found that Atf1 and Rst2 help each other stably ...
Molecular & Computational biology
Sep 13, 2021
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49
Researchers from Skoltech and their colleagues have optimized data analysis for a common method of studying the 3-D structure of DNA in single cells of a Drosophila fly. The new approach allows the scientists to peek with ...
Biotechnology
Jan 12, 2021
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5
How do molecules involved in activating our immune system discriminate between our own DNA and foreign pathogens? Researchers from the Thomä group, in collaboration with the EPFL, deciphered the structural and functional ...
Molecular & Computational biology
Nov 26, 2020
0
178
In eukaryotic cells, the genomic DNA is hierarchically packaged by histones into chromatin. Chromatin structure and its plasticity play an important role in the activation and silencing of gene transcription, and determine ...
Cell & Microbiology
Jul 29, 2020
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18
The genetic information within cells makes individuals unique. The cell nucleus has a complex structure that harbors this genetic information. The main component of the nucleus is chromatin, an intercalated pool of genes ...
Biotechnology
May 12, 2020
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6
The DNA of a single cell is two to three meters long end-to-end. To fit in the nucleus and function correctly, DNA is packaged around specialized proteins. These DNA-protein complexes are called nucleosomes, and they are ...
Biotechnology
Nov 21, 2019
0
126
The genome is not just a linear sequence of letters, but is also compartmentalized into a specifically tailored chromatin structure within cell nuclei. This three-dimensional genomic structure is fundamental, given that it ...
Cell & Microbiology
Jul 10, 2019
0
0
