DNA with a twist: Discovery could further antibiotic drug development
Scientists reveal how a 'molecular machine' in bacterial cells prevents fatal DNA twisting, which could be crucial in the development of new antibiotic treatments.
Scientists reveal how a 'molecular machine' in bacterial cells prevents fatal DNA twisting, which could be crucial in the development of new antibiotic treatments.
Biochemistry
Nov 22, 2018
2
150
Understanding how and when cells divide is important to figuring out everything from how cancers grow to why some mammals are able to get so big. A new study of E. coli cell data, published November 7 in Science Advances, ...
Cell & Microbiology
Nov 7, 2018
0
72
Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein ...
Cell & Microbiology
Oct 1, 2018
0
70
A new method allows researchers to systematically identify specialized proteins that unpack DNA inside the nucleus of a cell, making the usually dense DNA more accessible for gene expression and other functions. The method, ...
Cell & Microbiology
Jul 12, 2018
2
128
Viruses have been infecting all forms of life – from single-celled bacteria to humans – for as long as there has been life on Earth. Because of this, ancient mechanisms of virus resistance co-exist in our bodies alongside ...
Cell & Microbiology
Apr 19, 2018
0
79
Researchers may be able to stop the replication of Ebola virus by mutating its most important protein, according to a paper published in the Journal of Biological Chemistry.
Biochemistry
Mar 12, 2018
0
19
Human cells divide and create new cells throughout life. In this process, a steady—even rhythmic—supply of DNA building blocks is needed to create new DNA. Now researchers from the University of Copenhagen are the first ...
Biotechnology
Nov 10, 2017
1
492
DNA replication is among life's most important processes, providing a way for an organism's genetic material to be reproduced so it can be passed from cell to cell. For the first time, scientists have characterized that process ...
Cell & Microbiology
Sep 21, 2017
0
128
Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more compact than at any ...
Cell & Microbiology
Sep 14, 2017
0
342
Cell division is key for renewing the cells in our tissues and organs. There are two particular processes in which cell division is crucial: embryonic development and tumorigenesis. A fault in the process that copies DNA ...
Cell & Microbiology
Aug 16, 2017
0
20