Unveiling the mechanism protecting replicated DNA from degradation

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein ...

Finding the proteins that unpack DNA

A new method allows researchers to systematically identify specialized proteins that unpack DNA inside the nucleus of a cell, making the usually dense DNA more accessible for gene expression and other functions. The method, ...

Mutating Ebola's key protein may stop replication

Researchers may be able to stop the replication of Ebola virus by mutating its most important protein, according to a paper published in the Journal of Biological Chemistry.

Scientists unravel mysteries of DNA replication in corn

DNA replication is among life's most important processes, providing a way for an organism's genetic material to be reproduced so it can be passed from cell to cell. For the first time, scientists have characterized that process ...

How does a cell maintain its identity during replication?

Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more compact than at any ...

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