Dissecting the structural secrets of the inactive X chromosome

Cell biologists from RIKEN have provided an unprecedented glimpse into the distinctive features of an unusual chromosome—the inactivated X chromosome copy carried by every female cell. The findings are published in the ...

Team proposes a new view on euchromatin in the cell

Scientists studying cells have long held the view that euchromatin, the part of chromatin that is made up of genes and is genetically active, is open and can be transcribed. A research team, looking at new evidence from genomics ...

Study identifies new mechanisms driving genomic instability

A recent Northwestern Medicine study published in the Journal of Cell Biology has identified new mechanisms that cause genomic or chromosomal instability during cell division, findings that may improve the development of ...

Researchers shed new light on the motor of DNA replication

DNA replication is the process whereby cells make an exact copy of their DNA before cell division. A key part of the intricate DNA replication machinery is a molecular motor called CMG, which has the vital task of separating ...

DNA packaging supports cell division, finds study

The DNA molecule is located in the cell nucleus as a densely packed complex of DNA and protein, known as chromatin. Wrapped in sections around a core of special proteins known as histones, the DNA forms so-called nucleosomes, ...

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