Scientists unwind mystery behind DNA replication

The molecules of life are twisted. But how those familiar strands in DNA's double helix manage to replicate without being tangled up has been hard to decipher. A new perspective from Cornell physicists is helping unravel ...

How chromosomes change their shape during cell differentiation

The human genome is made up of 46 chromosomes, each of which has a length of about 100 to 200 million base pairs, the building blocks of the DNA double helix. Even during interphase, the period in between the cell division ...

A catalog of DNA replication proteins

Maintenance of genome integrity—and prevention of diseases such as cancer—requires complete and faithful replication of the genome every cell division cycle.

Detailed map shows how viruses infect humans

Biologists at Columbia University Vagelos College of Physicians and Surgeons have leveraged a computational method to map protein-protein interactions between all known human-infecting viruses and the cells they infect. The ...

DNA replication machinery captured at atom-level detail

July 15, 2019) Life depends on double-stranded DNA unwinding and separating into single strands that can be copied for cell division. St. Jude Children's Research Hospital scientists have determined at atomic resolution the ...

New progress in developing an animal model of hepatitis C

Small differences in a liver cell protein have significant impacts on hepatitis C virus replication in mice and humans, findings that could facilitate the development of a mouse model of the infection. The report, led by ...

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Self-replication

Self-replication is any process by which a thing might make a copy of itself. Biological cells, given suitable environments, reproduce by cell division. During cell division, DNA is replicated and can be transmitted to offspring during reproduction. Biological viruses can reproduce, but only by commandeering the reproductive machinery of cells through a process of infection. Computer viruses reproduce using the hardware and software already present on computers.

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