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Glycosylation—mapping uncharted territory

Whereas major inroads have been made into genomics, metabolomics, or protein and lipid research, glycosylation remains largely unexplored at the proteome scale. There are limited technologies for profiling the complex glycoproteome. ...

dateSep 21, 2017 in Cell & Microbiology
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Ricin only lethal in combination with sugar

The plant toxin ricin is one of the most poisonous naturally occurring proteins, making it an extremely dangerous bioweapon. Ricin attacks have made headlines a number of times over the years, including the spectacular "umbrella ...

dateSep 20, 2017 in Cell & Microbiology
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Sugary secrets of a cancer-related protein

The proteins in human cells are extensively decorated with different types of sugars, a phenomenon called glycosylation. These modifications greatly increase the diversity of protein structure and function, affecting how ...

dateSep 15, 2017 in Biochemistry
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