In the cell nucleus, histones play a crucial role packaging DNA into chromatin. Histones are however very sticky to both DNA and RNA, so to ensure they are transported to the cell nucleus after synthesis and bind to the right ...
Cell & Microbiology
Apr 14, 2021
0
18
DNA sequencing has become so common, few realize how hard it is to even extract a single molecule of DNA from a biological sample.
Bio & Medicine
Apr 6, 2021
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84
Nestled deep in the nucleus of each of your cells is what seems like a magic trick: Six feet of DNA is packaged into a tiny space 50 times smaller than the width of a human hair. Like a long, thin string of genetic spaghetti, ...
Molecular & Computational biology
Jan 28, 2021
0
19
Our bodies often dispatch stem cells to mend or replace biological damage, but how these repair agents make their way through dense tissue to arrive at the scene had been a mystery. "How stem cells squeeze through tissue ...
Cell & Microbiology
Jan 11, 2021
0
42
How do molecules involved in activating our immune system discriminate between our own DNA and foreign pathogens? Researchers from the Thomä group, in collaboration with the EPFL, deciphered the structural and functional ...
Molecular & Computational biology
Nov 26, 2020
0
178
Researchers at the Institut national de la recherche scientifique (INRS), in collaboration with American scientists, have discovered a new parvovirus strategy for reaching the cell nucleus, where they reproduce. The results ...
Cell & Microbiology
Sep 24, 2020
0
80
The stem cells tasked with creating and maintaining biological tissues have a difficult job. They have to precisely divide to form new specialized cells, which are destined to different fates even though they contain identical ...
Cell & Microbiology
Sep 17, 2020
0
136
In higher organisms, detection of DNA in the cytoplasm triggers an immune reaction. The enzyme that senses "misplaced" DNA is also found in the nucleus, but nuclear DNA has no such effect. LMU researchers now report why that ...
Molecular & Computational biology
Sep 11, 2020
0
32
Using an artificial intelligence (AI) cell classification technique, Northwestern Medicine investigators found that viruses can control structural and genetic polarity inside the cell nucleus. The findings, published in Nature, ...
Cell & Microbiology
Sep 10, 2020
0
39
Viruses multiply by injecting their DNA into a host cell. Once it enters the intracellular fluid, this foreign material triggers a defense mechanism known as the cGAS-STING pathway. The protein cyclic GMP-AMP Synthase (cGAS), ...
Cell & Microbiology
Aug 13, 2020
0
320
