Mathematical modeling shows why animals see at night

Nocturnal and diurnal mammals see the same—but only for a brief time. When mice are born, the chromatin in the cells of their eyes has a diurnal structure. Day by day, the layout of this chromatin slowly inverts, allowing ...

Upcycling of proteins protects DNA from parasites

Of the three billion base pairs in the human genome, less than two percent contain the information encoding the ~20,000 proteins. That is, because at least half of our genetic material originated from selfish genetic elements ...

Gatekeepers of the genome

Transcription factors control gene activation in cells. By binding to specific segments of DNA, they enable the blueprints that code for cellular proteins to be produced. But how are such factors themselves regulated?

New insight into microRNA function can give gene therapy a boost

Scientists at the University of Eastern Finland and the University of Oxford have shown that small RNA molecules occurring naturally in cells, i.e. microRNAs, are also abundant in cell nuclei. Previously, microRNAs were mainly ...

New function for the nucleolus

The nucleolus is a well-known structure in the cell nucleus that is easily visible under a light microscope. This nuclear structure is known to be the site of ribosome production. A new study shows that the nucleolus is also ...

Applying the Goldilocks principle to DNA structure

The Goldilocks of fairy-tale fame knew something about porridge. It needed to be just right—neither too hot nor too cold. Same with furniture—neither too hard nor too soft. In a different context, scientists at UC San ...

Research uncovers elusive process essential to plant greening

Despite how essential plants are for life on Earth, little is known about how parts of plant cells orchestrate growth and greening. By creating mutant plants, UC Riverside researchers have uncovered a cellular communication ...

How the cell protects itself

The cell contains transcripts of genetic material, which migrate from the cell nucleus to another part of the cell. This movement protects the genetic transcripts from the recruitment of "spliceosomes." If this protection ...

What organizes the genome in the nucleus?

Spatial separation of active from inactive fractions of the genome in the cell nucleus is crucial for gene expression control. A new study uncovers leading mechanisms of such separation and turns our picture of the nucleus ...

page 16 from 35