What organizes the genome in the nucleus?

Spatial separation of active from inactive fractions of the genome in the cell nucleus is crucial for gene expression control. A new study uncovers leading mechanisms of such separation and turns our picture of the nucleus ...

Mammoth moves: frozen cells come to life, but only just

A team of scientists in Japan has successfully coaxed activity from 28,000-year-old cells from a frozen mammoth implanted into mouse cells, but the woolly mammal is unlikely to be walking among us soon.

Nucleus-specific X-ray stain for 3-D virtual histology

Histology is used to identify structural details of tissue at the microscale in the pathology lab, but analyses remain two-dimensional (2D) as they are limited to the same plane. Nondestructive 3D technologies including X-ray ...

Genome-wide rules of nucleosome phasing in drosophila

LMU researchers have, for the first time, systematically determined the positioning of the packing units of the fruit fly genome and discovered a new protein that defines their relationship to the DNA sequence.

Plasma from lasers can shed light on cosmic rays, solar eruptions

Lasers that generate plasma can provide insight into bursts of subatomic particles that occur in deep space, scientists have found. Such findings could help scientists understand cosmic rays, solar flares and solar eruptions—emissions ...

DNA dominos on a chip

Normally, individual molecules of genetic material repel each other. However, when space is limited DNA molecules must be packed together more tightly. This case arises in sperm, cell nuclei and the protein shells of viruses. ...

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