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Intoxicatingly light-sensitive

ETH chemists have synthesised several variants of THC, the active ingredient in cannabis. Its structure can be altered with light, and the researchers have used this to create a new tool that can be used to more effectively ...

dateJan 11, 2018 in Biochemistry
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Macrophage nanosponges could keep sepsis in check

A team of researchers at the University of California San Diego has developed macrophage "nanosponges" that can safely absorb and remove molecules from the bloodstream that are known to trigger sepsis. These macrophage nanosponges, ...

dateJan 04, 2018 in Bio & Medicine
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A spring-loaded sensor for cholesterol in cells

Although too much cholesterol is bad for your health, some cholesterol is essential. Most of the cholesterol that the human body needs is manufactured in its own cells in a synthesis process consisting of more than 20 steps. ...

dateDec 07, 2017 in Biochemistry
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How ribosomes shape the proteome

Cells are crowded with macromolecules, which limits the diffusion of proteins, especially in prokaryotic cells without active transport in the cytoplasm. While investigating the relationship between crowding, ionic strength ...

dateDec 06, 2017 in Cell & Microbiology
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Nanodiscs catch misfolding proteins red-handed

When proteins misfold, accumulate and clump around insulin-producing cells in the pancreas, they kill cells. Now, researchers, including University of Michigan biophysicists, have obtained a structural snapshot of these proteins ...

dateDec 06, 2017 in Bio & Medicine
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Structure of primary optogenetic tool revealed

An international team of researchers has determined the 3-D structure of channelrhodopsin 2, a membrane protein widely used in optogenetics to control nerve cells with light. Optogenetics is a relatively new technique that ...

dateNov 28, 2017 in Biotechnology
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