Figuring out how blank slate stem cells decide which kind of cell they want to be when they grow up—a muscle cell, a bone cell, a neuron—has been no small task for science.
Cell & Microbiology
Sep 8, 2014
0
0
Discovering the step-by-step details of the path embryonic cells take to develop into their final tissue type is the clinical goal of many stem cell biologists. To that end, Kenneth S. Zaret, PhD, professor of Cell and Developmental ...
Cell & Microbiology
May 19, 2011
1
0
Scientists often talk about cell fate and commitment in terms of mechanisms that control gene expression (transcription factors, chromatin remodeling, etc.). But by studying Diamond-Blackfan anemia (DBA), rare genetic blood ...
Cell & Microbiology
Mar 19, 2018
0
22
High-resolution gene expression maps have been combined with single-cell genomics data to create a new resource for studying how cells adopt different identities during mammalian development. The Spatial Mouse Atlas is the ...
Cell & Microbiology
Sep 7, 2021
0
16
Bioengineers at the University of California, San Diego have discovered that mouse embryos are contemplating their cellular fates in the earliest stages after fertilization when the embryo has only two to four cells, a discovery ...
Biotechnology
Nov 26, 2014
0
0
Both cell type and developmental stage can be deduced from measurements of chromatin accessibility in thousands of single cells, researchers at EMBL and the University of Washington show. They used this approach to uncover ...
Cell & Microbiology
Mar 14, 2018
0
19
The development of an adult organism starts with a fertilized egg that differentiates into hundreds of specialized cell types comprising tissues and organs. How these cell fate changes happen is a subject of research interest. ...
Cell & Microbiology
Oct 3, 2018
0
9
St. Jude Children's Research Hospital scientists have determined how a protein's disordered region serves as a molecular rheostat to help regulate cell survival.
Biochemistry
Mar 6, 2018
0
60
Every gene in the nucleus of an animal or plant cell is packaged into a beads-on-a-string like structure called nucleosomes: the DNA of the gene forms the string and a complex of proteins called histones forms the beads around ...
Biotechnology
Feb 11, 2013
0
0
(Phys.org) —Knowing virtually everything about how the body's cells make transitions from one state to another – for instance, precisely how particular cells develop into multi-cellular organisms – would be a major ...
Cell & Microbiology
Jul 1, 2013
0
0
