Stem cells ensure the development of tissues, their daily maintenance and their repair following injuries. One of the key questions in the field of stem cell biology is to define the different cell lineages in which stem ...
Cell & Microbiology
Jun 9, 2016
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50
Susan Gasser and her group at the FMI have identified in C. elegans a much sought-for anchor protein, a previously uncharacterized chromodomain protein called CEC-4 that directly sequesters inactive chromatin at the nuclear ...
Cell & Microbiology
Dec 2, 2015
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409
Toggling the functions of a protein that regulates gene expression during cellular reprogramming ensures cell fate conversion, an A*STAR study has found.
Cell & Microbiology
Nov 16, 2018
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7
Chromatin remodeling—the packaging and unpackaging of genomic DNA and its associated proteins—regulates a host of fundamental cellular processes including gene transcription, DNA repair, programmed cell death as well ...
Biochemistry
Nov 29, 2012
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0
Researchers have long thought that once a cell starts down its path of differentiation, growing into a skin cell or a liver cell or a neuron, that path could not be changed.
Cell & Microbiology
Jun 6, 2023
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38
The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments.
Cell & Microbiology
May 30, 2023
0
113
Northwestern Medicine investigators have discovered that mitochondria regulate essential cellular signaling for the development of epithelial cells in the lungs, cells which are crucial for the exchange of oxygen and carbon ...
Cell & Microbiology
Aug 10, 2023
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4
Stars, diamonds, circles: Rather than your average bowl of Lucky Charms, these are three-dimensional cell cultures generated by an exciting new digital microfluidics platform, the results of which have been published in Nature ...
Cell & Microbiology
Feb 26, 2014
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1
Johns Hopkins biologists have discovered that when biological signals hit cells in rhythmic waves, the magnitude of the cells' response can depend on the number of signaling cycles—not their strength or duration. Because ...
Cell & Microbiology
Mar 20, 2014
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0
Some 50 years have passed since scientists first proposed the so-called 'inside–outside model' of development, which holds that the inner cells of the early embryo eventually form all the definitive structures of the fetus, ...
Cell & Microbiology
Apr 10, 2013
0
0
