Researchers find 'protein-scaffolding' for repairing DNA damage

At the University of Copenhagen, researchers have discovered how some types of proteins stabilize damaged DNA and thereby preserve DNA function and integrity. This new finding also explains why people with inborn or acquired ...

Biologists discover source for boosting tumor cell drug sensitivity

DNA-damaging agents, or "DDAs," make up the most widely used group of cancer drugs. Yet their therapeutic success has been curtailed by drug resistance—either present in cancer cells from the disease onset or arising during ...

Fragmenting ions and radiation sensitizers

A new study using mass spectrometry is helping piece together what happens when DNA that has been sensitized by the oncology drug 5-fluorouracil is subjected to the ionising radiation used in radiotherapy.

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