Protein maintains order in the nucleus

Researchers in Freiburg identify a protein responsible for the correct arrangement of the chromosome centromeres in the nucleus.

Sall4 is required for DNA repair in stem cells

A protein that helps embryonic stem cells (ESCs) retain their identity also promotes DNA repair, according to a study in The Journal of Cell Biology. The findings raise the possibility that the protein, Sall4, performs a ...

Screen could offer better safety tests for new chemicals

It's estimated that there are approximately 80,000 industrial chemicals currently in use, in products such as clothing, cleaning solutions, carpets, and furniture. For the vast majority of these chemicals, scientists have ...

Stem cells replace stroke-damaged tissue in rats

Effective stem cell treatment for strokes has taken a significant step forward today as scientists reveal how they have replaced stroke-damaged brain tissue in rats.

Scientists identify protein profiles of DNA repair

During each cell division, more than 3.3 billion base pairs of genomic DNA have to be duplicated and segregated accurately to daughter cells. But what happens when the DNA template is damaged in such a way that the replication ...

Structural knowledge of the DNA repair complex

New Danish research provides mechanistic insight into how DNA is monitored and repaired if damage occurs. The results may eventually help to improve the treatment of certain types of cancer, as the DNA repair complex provides ...

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