Scientists and clinicians often encounter road blocks in designing specific treatments for diseases like cancer or developmental disorders because proteins that regulate cell functions through complex mechanisms are misunderstood.
A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells. The cryo-EM ...
DNA has been used as a 'molecular building block' to construct synthetic bio-inspired pores which will improve the way drugs are delivered and help advance the field of synthetic biology, according to scientists from UCL ...
University of Manchester scientists have discovered a cluster of 60 proteins that allow the body's cells to react to their environment and communicate with each other.
Scientists have found a new function of the nuclear membrane, the envelope that encases and protects DNA in the nucleus of a cell - it fixes potentially fatal breaks in DNA strands.
An enzyme called telomerase plays a significant role in aging and most cancers, but until recently many aspects of the enzyme's structure could not be clearly seen.
Scientists at the Universities of Manchester and Nottingham have been funded to develop a gel that will match many of the biological structures of human breast tissue, to advance cancer research and reduce animal testing.
Tumor markers are biological substances, usually proteins, that provide early indication of cancerous or benign tumors in the body.
Rice University scientists have developed a practical method to synthesize chemical building blocks widely used in drug discovery research and in the manufacture drugs and dyes.
The "friendly" bacteria inside our digestive systems are being given an upgrade, which may one day allow them to be programmed to detect and ultimately treat diseases such as colon cancer and immune disorders.