Enzyme biofactories to enhance cord blood transplants
A new way of producing an enzyme called fucosyltransferase VI (FTVI) in the lab could help enhance the therapeutic potential of cord blood transplants.
A new way of producing an enzyme called fucosyltransferase VI (FTVI) in the lab could help enhance the therapeutic potential of cord blood transplants.
Biochemistry
Oct 22, 2020
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9
Using specialized nanoparticles, MIT engineers have developed a way to turn off specific genes in cells of the bone marrow, which play an important role in producing blood cells. These particles could be tailored to help ...
Bio & Medicine
Oct 5, 2020
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597
Stem cells that form the blood and immune system, so-called hematopoietic stem cells (HSCs), have important applications in the treatment of blood cancers and other diseases of the immune system. Through blood stem cell transplantation, ...
Molecular & Computational biology
Sep 17, 2020
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2
Blood platelets, also called thrombocytes, are all-important cells with a diameter of between only 0.0015 and 0.003 millimeters. They have the task of resealing injuries to the blood vessels as quickly as possible, for which ...
Biochemistry
Jul 30, 2020
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10
Recently, a research team led by Dr. Liu Qingsong and Dr. Liu Jing from High Magnetic Field Laboratory of the Chinese Academy of Sciences has discovered a novel FLT3-ITD mutation-selective kinase inhibitor CHMFL-FLT3-362, ...
Molecular & Computational biology
May 20, 2020
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3
Silkworms are useful for more than just making strong and absorbent strings of silky thread for the textiles industry. A group of KAUST scientists has now coaxed these grub-like insects into making the human form of E-selectin, ...
Biochemistry
Mar 16, 2020
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12
A Loughborough University Ph.D. student has provided new insight into how breast cancer cells interact with cells in our body by using a novel 3-D model.
Biochemistry
Feb 18, 2020
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46
Researchers from the European Molecular Biology Laboratory (EMBL) and the German Cancer Research Center (DKFZ) in Heidelberg, Germany, have developed new methods to reveal the three-dimensional organization of bone marrow ...
Cell & Microbiology
Dec 23, 2019
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41
Multiple myeloma is a type of blood cancer in which malignant plasma cells, a type of white blood cell, accumulate in the bone marrow. This leads to bone destruction and failure of the marrow, which in healthy individuals, ...
Biochemistry
Nov 19, 2019
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25
hematopoietic stem cells (HSCs) are responsible for the constant replenishment of all blood cells throughout life. One of the major challenges in regenerative medicine is to produce tailor-made HSCs to replace the defective ...
Cell & Microbiology
Nov 4, 2019
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46