Researchers at the University of California, San Diego School of Medicine have identified a microRNA molecule as a surprisingly crucial player in managing cell survival and growth. The findings, published in the October 7 ...
Cell & Microbiology
Oct 7, 2014
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A family of nutrient-sensing enzymes, dubbed Rag GTPases, modulates the activity of the mTORC1 protein complex, whose inhibition is essential for autophagy and survival in newborn mammals. One enzyme, RagA, has been found ...
Cell & Microbiology
Dec 23, 2012
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Programmed cell death (PCD) is a highly regulated process that occurs in all animals and plants as part of normal development and in response to the environment. New research published in BioMed Central's open access journal ...
Cell & Microbiology
Jul 24, 2012
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Autophagy is a self-eating process for recycling and rejuvenating cellular organelles and components. Intracellular calcium dynamics has been shown to be essential for the initiation of the autophagy process.
Cell & Microbiology
Mar 6, 2024
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Even the genes and proteins that have been most closely studied are still far from having given up all their secrets. Like a Swiss Army knife, they have many different, often unknown functions.
Cell & Microbiology
Feb 21, 2024
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A research group led by Professor Nobuo Noda of Hokkaido University has reconstituted the membrane invagination process required to form autophagosomes in vitro for the first time, showing that this process is mediated by ...
Molecular & Computational biology
Dec 20, 2023
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The link between air pollution and lung disease has long been recognized. Now a new USC study reveals one biological process that may be behind that link—a discovery which could provide new insights on better ways to treat ...
Molecular & Computational biology
May 17, 2023
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Junior Associate Professor Kazuo Takayama and his research team used human airway organoids to screen autophagy-related compounds and found cycloheximide and thapsigargin to show strong antiviral effects against SARS-CoV-2. ...
Biochemistry
Apr 14, 2023
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A research group led by Prof. Zhang Hong from the Institute of Biophysics of the Chinese Academy of Sciences has demonstrated that RNAs act as a switch to change the fate of phase-separated protein condensates from autophagic ...
Cell & Microbiology
Apr 6, 2023
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A midlife career change is hard to pull off, because it can involve reinventing yourself and adopting a completely new professional role. Now, researchers from Japan show that some plant cells get a helping hand from autophagy ...
Plants & Animals
Jul 6, 2022
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