A team of researchers has developed a new method to screen FDA-approved drugs to determine if they could be repurposed or improved to help patients with a rare, debilitating disease of the nervous system.
Biochemistry
Feb 16, 2023
0
24
Metastases occur when cancer cells leave a primary tumor and spread throughout the body. For this to happen, they have to break connections with neighboring cells and migrate to other tissues. Both processes are promoted ...
Cell & Microbiology
Jan 24, 2023
0
11
Bacterial pathogens like Salmonella, Shigella, Listeria and many others exploit the protein skeleton of the cells they infect in order to spread throughout the host. However, how is this so-called cytoskeleton of host cells ...
Cell & Microbiology
Dec 15, 2022
0
51
A recent study led by Assistant Professor of Gerontology Ryo Sanabria has identified a key protein that helps regulate the actin cytoskeleton, a scaffold of proteins within cells that makes their proper structure and function ...
Cell & Microbiology
Dec 12, 2022
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5
Toxins released by a type of bacteria that cause diarrheal disease hijack cell processes and force important proteins to assemble into "roads to nowhere," redirecting the proteins away from other jobs that are key to proper ...
Molecular & Computational biology
Nov 18, 2022
0
139
In a new study, University of Maryland researchers have demystified the process by which cells receive their shape—and it all starts with a protein called actin.
Cell & Microbiology
Nov 4, 2022
0
88
Actin filaments are protein fibers that make up the internal skeleton of the cell. As active elements of our cells, actin filaments support the cell's fusion, movement and are involved in many other cellular processes. Importantly, ...
Cell & Microbiology
Oct 26, 2022
0
7
Inside the leading edge of a crawling cell, intricate networks of rod-like actin filaments extend toward the cell membrane at various angles, lengthening protein by protein. Upon impact, the crisscrossing rods glance off ...
Biochemistry
Oct 26, 2022
0
35
"I'm a professional pin-in-a-haystack seeker," geneticist Thijn Brummelkamp responds when asked why he excels at tracking down proteins and genes that other people did not find, despite the fact that some have managed to ...
Cell & Microbiology
Sep 29, 2022
0
34
During development, the cells of an embryo divide until a fully functional organism emerges. One component of the cell is especially important during this process: the cell cortex. This fine network of hair-like filament ...
Cell & Microbiology
Sep 16, 2022
0
22
