Toxins force construction of 'roads to nowhere'

Toxins released by a type of bacteria that cause diarrheal disease hijack cell processes and force important proteins to assemble into "roads to nowhere," redirecting the proteins away from other jobs that are key to proper ...

Molecular tug-of-war gives cells their shape

In a new study, University of Maryland researchers have demystified the process by which cells receive their shape—and it all starts with a protein called actin.

New evidence of biochemical states and force working in concert

Inside the leading edge of a crawling cell, intricate networks of rod-like actin filaments extend toward the cell membrane at various angles, lengthening protein by protein. Upon impact, the crisscrossing rods glance off ...

'Mystery gene' matures the skeleton of the cell

"I'm a professional pin-in-a-haystack seeker," geneticist Thijn Brummelkamp responds when asked why he excels at tracking down proteins and genes that other people did not find, despite the fact that some have managed to ...

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