Reimagining drugs for a rare brain disorder

A team of researchers has developed a new method to screen FDA-approved drugs to determine if they could be repurposed or improved to help patients with a rare, debilitating disease of the nervous system.

Actin found to affect the spread of cancer in several ways

Metastases occur when cancer cells leave a primary tumor and spread throughout the body. For this to happen, they have to break connections with neighboring cells and migrate to other tissues. Both processes are promoted ...

Toxins force construction of 'roads to nowhere'

Toxins released by a type of bacteria that cause diarrheal disease hijack cell processes and force important proteins to assemble into "roads to nowhere," redirecting the proteins away from other jobs that are key to proper ...

Molecular tug-of-war gives cells their shape

In a new study, University of Maryland researchers have demystified the process by which cells receive their shape—and it all starts with a protein called actin.

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Actinopterygii

The Actinopterygii /ˌæktɨnɒptəˈrɪdʒi.aɪ/ or ray-finned fishes constitute a class or sub-class of the bony fishes.

The ray-finned fishes are so called because they possess lepidotrichia or "fin rays", their fins being webs of skin supported by bony or horny spines ("rays"), as opposed to the fleshy, lobed fins that characterize the class Sarcopterygii which also, however, possess lepidotrichia. These actinopterygian fin rays attach directly to the proximal or basal skeletal elements, the radials, which represent the link or connection between these fins and the internal skeleton (e.g., pelvic and pectoral girdles).

In terms of numbers, actinopterygians are the dominant class of vertebrates, comprising nearly 96% of the 25,000 species of fish. They are ubiquitous throughout fresh water and marine environments from the deep sea to the highest mountain streams. Extant species can range in size from Paedocypris, at 8 millimetres (0.31 in), to the massive Ocean Sunfish, at 2,300 kilograms (5,100 lb), and the long-bodied Oarfish, to at least 11 metres (36 ft).

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