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Bio & Medicine May 16, 2024

Nanocarriers loaded with DNA relieve back pain, repairs damaged disk in mice

Disk-related back pain may one day meet its therapeutic match: Gene therapy delivered by naturally derived nanocarriers that, a new study shows, repairs damaged disks in the spine and lowers pain symptoms in mice.

Bio & Medicine May 15, 2024

Engineering a new color palette for single-molecule imaging

Researchers often study biomolecules such as proteins or amino acids by chemically attaching a "fluorophore," a sensitive molecule that absorbs and re-emits energy from light.

Biotechnology Jun 17, 2024

Scientists modify function of common enzymes by hacking genetics, could improve cancer treatments

Researchers are using the Canadian Light Source at the University of Saskatchewan to study how enzymes found in all forms of life (called ribonucleases) can be modified to work to our advantage. This technology could have ...

Molecular & Computational biology Jun 14, 2024

Study explores how key gene modulates terpene aroma in grapes

A study explores the ethylene-responsive gene VviERF003's influence on glycosylated monoterpenoid synthesis in grapes, which are pivotal for the fruity and floral notes in wines. Understanding this genetic regulation provides ...

Ecology May 16, 2024

Study shows regenerating worms have genetic control over their algal partners

Many organisms are far more complex than just a single species. Humans, for example, are full of a variety of microbes. Some creatures have even more special connections, though.

Biochemistry May 23, 2024

A fungus converts cellulose directly into a novel platform chemical

The fungus Talaromyces verruculosus can produce the chemical erythro-isocitric acid directly from cheap plant waste, thus making it interesting for industrial utilization.

Bio & Medicine Jun 18, 2024

Lung-targeting lipid nanoparticles with CRISPR components successfully treat cystic fibrosis mouse models

A team of medical researchers from the University of Texas Southwestern Medical Center, Case Western Reserve University School of Medicine and ReCode Therapeutics has developed a way to send gene-editing tools to the lungs ...

Plants & Animals May 22, 2024

Research improves multiplex mutagenesis to increase experimental efficiency in plant genome editing

CRISPR/Cas9 remains the most powerful tool to generate mutations in plant genomes. Studying the various combinations of mutations has significantly increased the scale of experimental setups, necessitating more space to grow ...

Molecular & Computational biology May 20, 2024

The genetic interplay in Impatiens downy mildew: A transcriptome-based approach to enhancing disease resistance

A research team has meticulously analyzed the transcriptional response of Impatiens walleriana to Plasmopara obducens infection, revealing between 3,000 and 4,500 differentially expressed transcripts at various stages of ...

Plants & Animals Jun 7, 2024

A protein that enables smell in ants—and stops cell death

While smell plays a considerable role in the social interactions of humans—for instance, signaling fear or generating closeness—for ants, it is vitally important. Researchers from New York University and the University ...

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