See also stories tagged with Extracellular matrix
Scientists have long sought to develop drug therapies that can more precisely diagnose, target and effectively treat life-threatening illness such as cancer, cardiovascular and autoimmune diseases. One promising approach ...
"The winner takes it all, the loser standing small"—that's not just true in the famous ABBA song, but also in animal development. Frequently, a group of cells starts out all being the same. But then one cell puts the brake ...
In bone tissue engineering (BTE), 3-D printing is a reliable and customizable method used to repair bone defects by producing biomimetic tissue scaffolds. In a recent study published online on Tissue Engineering Part A (Mary ...
Liver-on-a-chip cell culture devices are attractive biomimetic models in drug discovery, toxicology and tissue engineering research. To maintain specific liver cell functions on a chip in the lab, adequate cell types and ...
The ability of cells to adhere to each other and to their environment is the basis for multicellular life. Adhesion occurs via diverse receptors at the surface of cells that bind to specific ligands in their surroundings. ...
Why do distinct species have different proteins? Is there a key that allows eukaryotic cells to produce proteins involved in multicellularity that are mostly absent in prokaryotes? These are some of the questions addressed ...
When humans experience stress, their inner turmoil may not be apparent to an outside observer. But many animals deal with stressful circumstances—overcrowded conditions, not enough food—by completely remodeling their bodies. ...
Materials such as poly(ε-caprolactone) are used as scaffolds in bone tissue engineering, but their inherent hydrophobicity and surface smoothness can impair cell attachment, proliferation and differentiation in the lab, or ...
The cellular and molecular mechanisms of magnetic stimulation-based bone regeneration require further understanding at present. To evaluate the phenomenon in the lab, a three-dimensional (3-D) native collagen model was recently ...
A multi-disciplinary team consisting of NUS biophysicists along with scientists from New York University and National Institutes of Health have discovered that the protein Anosmin1 controls the diffusion of fibroblast growth ...
