Search results for CRISPR

Biotechnology Oct 28, 2022

Breakthrough in CRISPR research may lead to more effective and safer gene editing

10 years ago we saw a breakthrough in modern biology.

Biochemistry Oct 27, 2022

Team develops a prodrug form of curcumin that shows anti-tumor effects without toxicities

Curcumin, a natural molecule related to turmeric, has been used to treat cancer patients in cancer clinical studies. While it has documented antitumor effects, challenges involving its chemistry have caused drug development ...

Cell & Microbiology Oct 24, 2022

Even good gene edits can go bad

A Rice University lab is leading the effort to reveal potential threats to the efficacy and safety of therapies based on CRISPR-Cas9, the Nobel Prize-winning gene editing technique, even when it appears to be working as planned.

Evolution Oct 21, 2022

Characterizing the cis-regulatory evolution of the gene WntA in nymphalid butterflies

A combined team of researchers from Cornell University and The George Washington University, has characterized the cis-regulatory evolution of the gene WntA in nymphalid butterflies. In their study, published in the journal ...

Biotechnology Oct 11, 2022

New CRISPR-Cas approach permits more precise DNA cleavage

A team led by investigators at Massachusetts General Hospital (MGH) has overcome a major constraint for cutting and editing DNA by CRISPR-Cas enzymes and other technologies. The recent innovation, which is published in Nature ...

Bio & Medicine Oct 6, 2022

New gene-editing platform broadens scope of use of CRISPR gene editing

A team of researchers at Northwestern University has devised a new platform for gene editing that could inform the future application of a near-limitless library of CRISPR-based therapeutics.

Molecular & Computational biology Sep 26, 2022

Multiplex gene editing rapidly customizes tomato cultivars with different fruit colors

A research group led by Prof. Li Chuanyou from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences (CAS) has developed a rapid breeding strategy to generate tomato lines with different ...

Biotechnology Sep 22, 2022

RNA-editing tool a fast, sensitive test for COVID-19

An engineered CRISPR-based method that finds RNA from SARS-CoV-2, the virus that causes COVID-19, promises to make testing for that and other diseases fast and easy.

Molecular & Computational biology Sep 20, 2022

Plant breeding: Using 'invisible' chromosomes to pass on packages of positive traits

The ideal crop plant is tasty and high-yielding while also being resistant to diseases and pests. But if the relevant genes are far apart on a chromosome, some of these positive traits can be lost during breeding. To ensure ...

Cell & Microbiology Sep 8, 2022

New approach more than doubles stem cell editing efficiency, researchers report

A Penn State-led team of interdisciplinary researchers has developed techniques to improve the efficiency of CRISPR-Cas9, the genome editing technique that earned the Nobel Prize in 2020. While CRISPR-Cas9 is faster, less ...

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