CRISPR-Cas has become somewhat of a superstar over the past decade as a gene editing tool with revolutionary potential, especially in the health sciences. Originally known as an immune defense in bacteria, naturally occurring ...
New research from Cornell offers insights into a line of CRISPR systems, which could lead to promising antiviral and tissue engineering tools in animal and plants.
A new variation of the CRISPR-Cas9 gene editing system makes it easier to re-engineer massive quantities of cells for therapeutic applications. The approach, developed at Gladstone Institutes and UC San Francisco (UCSF), ...
Recently, scientists from Shanxi Datong University and Chongqing University revealed that SlCMT4, which encodes a DNA methyltransferase responsible for de novo and non-CG methylation, plays an important role in diverse developmental ...
Microbial secondary metabolites, those molecules not essential for growth yet essential for survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE technologies.
Applying new CRISPR-based technology to a broad agricultural need, researchers at the University of California San Diego have set their aims on a worldwide pest known to decimate valuable food crops.
A recent study published in Nature Biotechnology revealed the development of high-fidelity Cas13 variants with markedly reduced collateral effects by mutagenesis and demonstrated the feasibility of hfCas13 for efficient on-target ...
Genome editing can cure diseases, boost food production and open vast new fields of scientific discovery. But to realize its full potential, scientists need to precisely describe the details of their genome editing attempts ...
CRISPR/Cas9 is a precise gene editing technique whose development by Jennifer A. Doudna and Emmanuelle Charpentier was recognized with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors," CRISPR allows ...
The circadian clock entrains rhythmic patterns in behavioral and physiological processes to temporally coordinate systemic metabolism with the rising and setting of the sun. In previous investigation on human subjects, sphingomyelins ...
