Search results for CRISPR

Cell & Microbiology Jul 9, 2024

A genome-wide screen in live hosts reveals new secrets of parasite infection

Apicomplexan parasites are a common cause of disease, infecting hundreds of millions of people each year. They are responsible for spreading malaria; cryptosporidiosis—a severe childhood diarrheal disease; and toxoplasmosis—a ...

Cell & Microbiology Jul 8, 2024

Novel strategy proposed for selectively targeting G-quadruplex at specific genome loci

DNA G-quadruplexes (G4s) are a type of quadruple helix structure formed by a continuous guanine-rich DNA sequence. Although DNA G4s are thought to be involved in various biological processes, in many cases their causative ...

Molecular & Computational biology Jun 27, 2024

A new CRISPR-driven technology for gene drive in plants

Weeds are a pesky irritant for most home gardeners, but in large agricultural settings, weeds can pose an especially deadly problem. For example, Amaranthus palmeri, known as Palmer's pigweed, has evolved in many areas to ...

Biotechnology Jun 25, 2024

Boosting 'natural killer' cell activity could improve cancer therapy

Yale researchers have uncovered a way to make a type of white blood cells known as natural killer cells—which kill infected, damaged, or malignant cells in the body—more effective against cancer. The approach, they say, could ...

Biotechnology Jun 21, 2024

Beyond CRISPR: seekRNA delivers a new pathway for accurate gene editing

Scientists at the University of Sydney have developed a gene-editing tool with greater accuracy and flexibility than the industry standard, CRISPR, which has revolutionized genetic engineering in medicine, agriculture and ...

Bio & Medicine Jun 18, 2024

Lung-targeting lipid nanoparticles with CRISPR components successfully treat cystic fibrosis mouse models

A team of medical researchers from the University of Texas Southwestern Medical Center, Case Western Reserve University School of Medicine and ReCode Therapeutics has developed a way to send gene-editing tools to the lungs ...

Plants & Animals Jun 17, 2024

Overriding Mendel's laws: Researchers develop plant gene drive system for enhanced trait inheritance

A collaborative research team has developed a plant gene drive system called CRISPR-Assisted Inheritance utilizing NPG1 (CAIN), which, according to the researchers, uses a toxin-antidote mechanism in the male germline to ...

Biotechnology Jun 15, 2024

Some CRISPR screens may be missing cancer drug targets

CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments, including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and ...

Cell & Microbiology Jun 13, 2024

Permanent gene edits to tardigrades help shed light on their amazing resilience

Some species of tardigrades are highly and unusually resilient to various extreme conditions fatal to most other forms of life. The genetic basis for these exceptional abilities remains elusive.

Biotechnology Jun 11, 2024

Scientists engineer yellow-seeded camelina with high oil output

Efforts to achieve net-zero carbon emissions from transportation fuels are increasing demand for oil produced by nonfood crops. These plants use sunlight to power the conversion of atmospheric carbon dioxide into oil, which ...

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