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Cell & Microbiology Dec 13, 2023

Research discovers that mice possess a natural gene therapy system

A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.

Cell & Microbiology Nov 29, 2023

Research reveals clever dosage control mechanism of biallelic genes

Have you ever wondered why we carry two copies of each chromosome in all of our cells? During reproduction, we receive one from each of our parents. This means that we also receive two copies, or alleles, of each gene—one ...

Molecular & Computational biology Nov 27, 2023

A novel quantification method for ribonucleotides, which are needed in almost all cellular processes

RNA (ribonucleic acid), which is made up of ribonucleotides, is a molecule found in all living organisms. RNA is thought to have probably preceded DNA in primordial life billions of years ago. RNA was eventually replaced ...

Cell & Microbiology Nov 24, 2023

Scientists reveal how RNA gets spliced correctly

To carry out all of life's functions, proteins must be produced from instructions carried by genes within DNA and delivered to the cell's protein-making machinery by messenger RNA.

Biotechnology Nov 17, 2023

Novel approaches for correcting gene expression insufficiency

A new molecular technology capable of binding to mRNA and regulating gene expression may offer a new avenue for treating diseases caused by haploinsufficiency, or the absence of one functional gene copy, according to a study ...

Cell & Microbiology Nov 1, 2023

New antimicrobial molecule shuts down bacterial growth without harming human cells

Scientists have shown how a molecule with broad-spectrum antibiotic activity works by disabling a process vital to bacterial growth without affecting the normal functioning of human cells. The journal mBio published the work, ...

Cell & Microbiology Oct 27, 2023

Intercellular messengers reveal themselves

The cells in our body continuously keep each other informed. They do this by exchanging, among other things, virus-like vesicles. Pascale Zimmermann's group, from the Department of Human Genetics, has been studying these ...

Biochemistry Oct 20, 2023

Broad-spectrum antiviral candidate targets dengue and SARS-CoV-2

A broad-spectrum antiviral drug candidate, 2-thiouridine, that targets positive-strand RNA viruses has been identified and characterized.

Molecular & Computational biology Oct 18, 2023

New method may accurately identify body fluids at crime scenes

Identifying different types of body fluids can help forensic experts reconstruct a crime scene, but it's difficult to do so. In a study published in Electrophoresis, researchers developed a method using two different types ...

Bio & Medicine Oct 16, 2023

Rational design of mRNA nanovaccine for cancer immunotherapy

Messenger RNA (mRNA) vaccines are revolutionizing the therapy of cancer. They can be flexibly developed in a short period of time, allowing transient expression of multiple antigens for safe and efficient immunization. A ...

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