Search results for CRISPR

Plants & Animals Jan 29, 2025

After inversion by CRISPR/Cas, the epigenetic state of plant chromosomes remains stable

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK Leibniz Institute (IPK) and the Karlsruhe Institute of Technology (KIT) has investigated how the chromosomal ...

Bio & Medicine Jan 28, 2025

Escaping the endosome: BEND lipids improve LNP mRNA delivery and gene editing

Every time a shuttle docks with the International Space Station (ISS), a delicate dance unfolds between the shuttle's docking system and its counterpart on the station. Thanks to international standards, these mechanisms ...

Biotechnology Jan 9, 2025

Scientists engineer CRISPR enzymes that evade immune system

The core components of CRISPR-based genome-editing therapies are bacterial proteins called nucleases that can stimulate unwanted immune responses in people, increasing the chances of side effects and making these therapies ...

Biotechnology Jan 8, 2025

Repairing a domestication mutation in tomato leads to an earlier yield

Genome editing with CRISPR-Cas is often associated with the induction of mutations. However, a team of researchers from the Swiss University of Lausanne now shows that it can also be used to repair natural mutations.

Evolution Dec 24, 2024

Fly vs. wasp: Stealing a defense move helps thwart a predator

In the continual arms race between parasites and their hosts, innovation was thought to be the key to a successful attack or defense that one-ups the competition. But sometimes, as in the corporate world, outright theft can ...

Cell & Microbiology Dec 23, 2024

Microbiome study finds bacteria in human gut rarely update their CRISPR defense systems

Within the human digestive tract are trillions of bacteria from thousands of different species. These bacteria form communities that help digest food, fend off harmful microbes, and play many other roles in maintaining human ...

Evolution Dec 19, 2024

Genetic mutations in parasites may lead to global spread of sleeping sickness

Parasites that cause the deadly illness known as sleeping sickness can spread beyond their native Africa as a result of mutations to key genes, a study shows.

Biotechnology Dec 19, 2024

CRISPR screening method uses colored nuclei to reveal key genes

The identification of genes involved in diseases is one of the major challenges of biomedical research. Researchers at the University of Bonn and the University Hospital Bonn (UKB) have developed a method that makes their ...

Biotechnology Dec 11, 2024

Q&A: Discovery opens up possibilities for new AI-developed antibiotic

A research team have recently published their article, "Rationally designed pooled CRISPRi-seq uncovers an inhibitor of bacterial peptidyl-tRNA hydrolase" in Cell Reports. In this study, the team created a collection of bacterial ...

Cell & Microbiology Dec 10, 2024

Weaponizing bacterial viruses to combat superbugs

Researchers from the University of Illinois have reported complementary discoveries that will improve scientists' understanding of immune systems in bacteria and equip clinicians with more effective options for treating antibiotic-resistant ...

page 17 from 40