Search results for CRISPR

Biotechnology Mar 12, 2025

Genome editing technique enables partial inhibition of gene function in crops

Researchers at Kumamoto University have successfully executed a practical trial of a new genome-editing technique that allows for the partial inhibition of essential gene function without causing lethality. This innovative ...

Biotechnology Mar 12, 2025

New technology puts a spatial lens on CRISPR screening

Recently, scientists have been able to explore gene circuitry in individual cells using methods that suppress particular genes and measure the impact on the expression of other genes. These methods, however, fail to capture ...

Cell & Microbiology Mar 11, 2025

BREX system's unique DNA recognition mechanism enhances bacterial antiviral defense

Bacteriophages, the most abundant life form on Earth, infect bacterial cells and influence the structure of the microbial community. To fend off phage attacks, bacteria have evolved their own defense tools, including the ...

Cell & Microbiology Mar 3, 2025

CRISPR-based method enhances detection of antibiotic resistance in wastewater

Antibiotic resistance is a global concern that threatens our ability to prevent and treat bacterial infections in humans and animals. To better monitor the emergence and spread of resistance, researchers at the Carl R. Woese ...

Plants & Animals Feb 19, 2025

CRISPR manipulation of UFO gene reveals complex plant flowering dynamics

Humans have appreciated the beauty of flowers for centuries. Yet, flowers aren't just aesthetically pleasing. They also play a crucial role in plant reproduction. In all plants, a well-studied gene with a curious name, Unusual ...

Biotechnology Feb 17, 2025

AcrVIB1: The unexpected anti-CRISPR protein that tightens RNA binding

The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to antiviral therapies and diagnostics. However, to safely harness their powers, scientists are searching for ...

Biotechnology Feb 17, 2025

NanoCas, a smaller version of CRISPR tested with a single AAV, delivers on-target results

Mammoth Biosciences researchers have developed NanoCas, an ultracompact CRISPR nuclease, demonstrating its ability to perform gene editing in non-liver tissues, including skeletal muscle, using a single adeno-associated virus ...

Biotechnology Feb 14, 2025

CRISPR system variant shows a novel DNA cleavage mechanism

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms.

Cell & Microbiology Feb 13, 2025

Gene editing approach sheds light on how mitochondria drive autophagy

Autophagy is the process by which cells digest and renew their internal structures, recycling damaged or malfunctioning proteins and organelles. By reusing these basic molecules, the cell gains the energy and resources needed ...

Biotechnology Feb 6, 2025

CRISPR technique helps reveal how bean genes could improve nitrogen fixation

Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume. They also have a "superpower" in the field: they are able to fix nitrogen to the soil, so they ...

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