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Biochemistry Feb 16, 2023

Researchers develop light-controlled drugs for future precision therapies against diseases such as cancer

Researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of Spanish National Research Council (CSIC) have developed a series of photosensitive molecule drugs that can be reversibly activated by external light, ...

Biochemistry Feb 2, 2023

Multiplication on, multiplication off: Targeting an enzymatic switch to develop oncology drugs

Researchers from the University of Illinois Urbana-Champaign and the University of Illinois Chicago have demonstrated a powerful new approach to small molecule drug development.

Bio & Medicine Feb 2, 2023

Noninvasive test can detect even trace elements of prostate cancer

Cedars-Sinai Cancer investigators have developed a new nanotechnology-based test that can detect and profile prostate cancers—even in microscopic amounts. Their work, published in the journal Nano Today, suggests that this ...

Cell & Microbiology Jan 24, 2023

Stunningly detailed blueprint revealed of viral genome replication machinery

RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell.

Biochemistry Jan 20, 2023

In a first, chemists synthesize ocean-based molecule that could fight Parkinson's

Organic chemists at UCLA have created the first synthetic version of a molecule recently discovered in a sea sponge that may have therapeutic benefits for Parkinson's disease and similar disorders. The molecule, known as ...

Cell & Microbiology Jan 18, 2023

How do human body–associated microbes spread? The transmission landscape of human microbiomes

The microbiome is a great ally of our health. It performs a fundamental role in the functioning of the immune and digestive systems, among many others. However, there is still very limited knowledge on how the bacteria and ...

Cell & Microbiology Jan 16, 2023

Understanding the alpha smooth muscle actin–driven foreign body response during wound healing

The foreign body response is a clinically relevant process that can lead to issues with biocompatibility in implanted medical devices due to fibrosis. While the inflammatory nature of the foreign body response is already ...

Molecular & Computational biology Jan 12, 2023

The proteins that fix (almost) everything

Proteins can make any inventor green with envy. It is proteins that make the body work. But when these same super-substances make mistakes, we may get sick with things like cancer or Alzheimer's disease. The job of researchers ...

Bio & Medicine Jan 10, 2023

New nanotransporter for drug delivery inside cells

A new study by the University of Barcelona has analyzed the viability of a new nanomolecule as drug delivery vehicle. The results, published in the journal Colloids and Surfaces B: Biointerfaces, show that liposomes designed ...

Biotechnology Jan 2, 2023

New method precisely locates gene activity and proteins across tissues

A new method can illuminate the identities and activities of cells throughout an organ or a tumor at unprecedented resolution, according to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and ...

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