The Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) in Berlin, Germany is one of the sixteen research centers of the Helmholtz Association of German Research Centres.

Website
https://www.mdc-berlin.de/
Wikipedia
https://en.wikipedia.org/wiki/Max_Delbr%C3%BCck_Center_for_Molecular_Medicine_in_the_Helmholtz_Association

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How proteins reshape cell membranes

Small "bubbles" frequently form on membranes of cells and are taken up into their interior. The process involves EHD proteins - a focus of research by Prof. Oliver Daumke of the MDC. He and his team have now shed light on ...

Mole rats are pain-free, thanks to evolution

African mole rats are insensitive to many kinds of pain. As an international research team led by the MDC's Gary Lewin reports in Science, this characteristic has allowed mole rats to populate new habitats. Thanks to a genetic ...

Circular RNA linked to brain function

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the current issue of Science, Nikolaus Rajewsky and his team at the ...

Reconstructing life at its beginning, cell by cell

After 13 rapid divisions a fertilized fly egg consists of about 6,000 cells. They all look alike under the microscope. However, each cell of a Drosophila melanogaster embryo already knows by then whether it is destined to ...

Genome editing: Efficient CRISPR experiments in mouse cells

In order to use the CRISPR-Cas9 system to cut genes, researchers must design an RNA sequence that matches the DNA of the target gene. Most genes have hundreds of such sequences, with varying activity and uniqueness in the ...

Reproducing the computational environments of experiments

Experiments increasingly rely on high-performance computing software. Differences in software environments can cause problems when those experiments need to be reproduced—so scientists at the MDC in Berlin are seeking a ...

Epigenetic mechanism appears to strongly influence healthy aging

Researchers at the Max Delbrueck Center for Molecular Medicine (MDC) have identified an epigenetic mechanism that appears to strongly influence healthy aging. It's a protein that controls muscle integrity, lifespan and levels ...

A complete cell atlas and lineage tree of the immortal flatworm

From one stem cell to many differentiated body cells: Scientists from the MDC in Berlin, along with collaborating researchers in Munich, have published a comprehensive lineage tree of a whole adult animal in the journal Science. ...

The art of folding mitochondrial membranes

Oliver Daumke's lab figures out how the inner membranes of mitochondria "get their groove" and assume the complex shapes they need to carry out crucial cellular functions.

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